Best Pizza Restaurants in Alphabet City
4 hand-picked restaurants, critic-reviewed and ranked
Last Updated: February 2026
Our Top Pick
Pizzana
Innovative, upscale pizzas with seasonal, locally sourced ingredients.
Notable Picks
#1
Pizzana
8.7
Modern, upscale pizzeria serving artisanal pizzas with fresh, seasonal ingredients.
Must-Try Dishes:
Margherita Pizza, Cacio e Pepe Pizza, Sausage & Broccoli Rabe Pizza
What Makes it Special: Innovative, upscale pizzas with seasonal, locally sourced ingredients.
8.4
Vibes:
Quick Bites Champions
Cheap Eats Budget Brilliance
Solo Dining Sanctuaries
Late Night Legends
A square-slice-first neighborhood shop that leans on crisp edges, a balanced red sauce, and a steady rotation of pies that hold up for grab-and-go. It’s best when you treat it like a slice bar: pick one classic, one topping-forward option, and keep the pace quick.
Must-Try Dishes:
Sicilian square slice, Vodka slice, Pepperoni square slice
What Makes it Special: Crisp, satisfying square slices built for fast, reliable slice decisions.
8.2
A thin-crust specialist where the appeal is crisp structure, clean toppings, and a dining-room pace that still feels casual. It’s strongest when you order two contrasting pies—one classic red-sauce, one topping-driven—and let the thin crust do the heavy lifting.
Must-Try Dishes:
Thin-crust Margherita, Arugula-topped thin-crust pie, Sausage and pepper thin-crust pie
What Makes it Special: Ultra-thin crust that stays crisp and toppings that stay balanced.
Worthy Picks
7.8
A true late-night utility shop on Avenue A—open deep into the night—where the pizza is the practical move when you need something hot and filling without a sit-down. Best when you keep it simple: one or two slices and you’re out, before the order turns into a long wait.
Must-Try Dishes:
Cheese slice, Vodka sauce slice, Pepperoni slice
What Makes it Special: Avenue A late-night hours with hot slices when most places close.