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Best Pizza Restaurants in Uptown

5 hand-picked restaurants, critic-reviewed and ranked

Last Updated: February 2026

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Our Top Pick
Spacca Napoli Pizzeria
Neapolitan technique that stays consistent at very high volume.

Notable Picks

$$ Uptown Italian, Pizza
A Neapolitan-focused pizzeria where the crust is the headline—soft center, blistered edge, and toppings that stay disciplined. Locals come for classic pies and a steady rotation of Italian imports, and it’s one of the most reliable “pizza night, no regrets” rooms in this part of town.
Must-Try Dishes: Margherita pizza, Prosciutto e rucola pizza, Tiramisu
What Makes it Special: Neapolitan technique that stays consistent at very high volume.
8.4
Uptown Italian, Pizza
A laid-back room with serious execution—Roman-leaning pizzas plus house-made pastas that keep it from being a one-trick pizzeria. It’s strongest when you split one oblong pizza and add one pasta, letting the kitchen show range without over-ordering.
Must-Try Dishes: Diavola-style pizza, Mezze maniche alla carbonara, Squid ink spaghetti with clams
What Makes it Special: Bib Gourmand-caliber pizza and pasta in an unfussy neighborhood room.
$$ Uptown Italian, Pizza
A big, sports-bar-style Italian spot that’s built around tavern-cut pizza with a loyal local following. The best play is to keep it simple—one classic pie plus one side—so the kitchen stays in its most repeatable lane.
Must-Try Dishes: Tavern-style thin crust (square-cut), Buffalo wings, Sausage pizza
What Makes it Special: Tavern-cut pizza in a high-TV, neighborhood tavern setting.

Worthy Picks

$ Uptown Pizza, Italian
A classic neighborhood pizza shop that leans into fast service, big slices, and familiar Chicago-area comfort. It shines when you order simply—thin crust or a slice-and-salad combo—so the value stays the headline.
Must-Try Dishes: Thin-crust sausage pizza, Pepperoni slice, Stuffed pizza
What Makes it Special: Big-slice, fast-service pizza that’s built for everyday cravings.
Uptown Pizza
A straightforward neighborhood counter built around no-fuss pies and takeout convenience. The best path here is one focused pizza—especially a sauce-and-topping combo you already know you like—because the strength is simple satisfaction, not maximal customization.
Must-Try Dishes: Buffalo chicken pizza, Pepperoni pizza, Cheese pizza
What Makes it Special: No-frills counter pizza that’s built to solve a quick craving.